Therapeutic use of antibodies and fragments thereof binding...

Details Therapeutic use of antibodies and fragments thereof binding... Therapeutic use of antibodies and fragments thereof binding...

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61K 39/395 (2006.01) A61P 31/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2467647

The present invention relates to the therapeutic use of molecules which bind and neutralize IFN-.gamma. in primates. More specifically, the present invention relates to the use of an anti-primate IFN-.gamma. antibody for preventing or treating diseases wherein IFN-.gamma. is pathogenic. The present invention further relates to a pharmaceutical composition comprising the anti- primate IFN-.gamma. antibody D9D10 for preventing or treating pathological reactions caused by IFN-.gamma..

La présente invention a pour objet l'utilisation thérapeutique de molécules qui se lient et neutralisent l'interféron gamma chez des primates. Plus spécifiquement, cette invention a trait à l'utilisation d'un anticorps de l'interféron gamma <= anti-primate >= permettant de prévenir ou de traiter des maladies, dans lesquelles l'interféron gamma est pathogène. En outre, cette invention concerne une composition pharmaceutique contenant un anticorps D9D10 de l'interféron gamma <= anti-primate >=, destinée à la prévention ou au traitement de réactions pathologiques causées par l'interféron gamma.

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