C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/08 (2006.01) A01N 43/90 (2006.01) C07H 19/01 (2006.01)
Patent
CA 2168843
The most thermodynamically stable crystalline form of the benzoic acid salt of 4"-deoxy-4"-epi-methylamino avermectin B1a-B1b as the hemihydrate is obtained by crystallization from organic solvents containing a controlled amount of water.
La forme cristalline la plus thermodynamiquement stable du sel d'acide benzoïque de 4"-désoxy-4"-épi-méthylamino avermectine B1a/B1b en tant que semi-hydrate est obtenue par cristallisation à partir de solvants organiques contenant une quantité contrôlée d'eau.
Cvetovich Raymond
Demchak Richard
Mccauley James A.
Varsalona Richard J.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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