C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/234, 260/308
C07D 277/20 (2006.01) C07D 277/24 (2006.01) C07D 277/28 (2006.01) C07D 277/30 (2006.01) C07D 277/56 (2006.01) C07D 277/60 (2006.01) C07D 277/64 (2006.01) C07D 277/82 (2006.01) C07D 417/12 (2006.01)
Patent
CA 1326034
Abstract: Disclosed are a thiazole derivative represented by the following formula, a pharmaceutically acceptable salt thereof and leukotriene antagonist containing the same as the active ingredients: Image wherein R1 and R2 each independently represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, a lower alkoxycarbonyl group or a substituted or unsubstituted phenyl group or cooperatively represent a tetramethylene group corresponding to a fused cyclohexane ring or a butadienylene group which is unsubstituted or substituted with a halogen atom, a lower alkoxy group, a lower alkoxycarbonyl group or an alkyl group having 1 to 3 carbon atoms corresponding to a fused benzene ring; R3, R4, R5 and R6 each independently represent a hydrogen atom, a hydroxyl group, a lower alkoxy group, an alkyl group having 1 to 3 carbon atoms or a halogen atom; A represents a linking group having 2 to 4 chain members; B represents a linking group having 2 to 5 chain members; and Q represents a carboxyl group, a lower alkoxy group, a hydroxyl group, an alkoxycarbonyl group having 2 to 6 carbon atoms or a 5-tetrazolyl group.
520544
Hayasi Yosio
Miida Hitoshi
Oguri Tomei
Shinoda Masaki
Takahashi Kazuo
Hayasi Yosio
Marks & Clerk
Miida Hitoshi
Mitsubishi Kasei Corporation
Oguri Tomei
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