Thiazolinones and oxazolinones and their use as ptp1b...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 277/42 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) A61P 3/10 (2006.01) C07D 263/48 (2006.01) C07D 413/06 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07F 9/6539 (2006.01)

Patent

CA 2622518

The present invention encompasses; the novel substituted heterocyclic compounds represented by formula (I) or their pharmaceutically acceptable salts, wherein the substituents in formula (I) have the meanings as defined in the specification. The invention also encompasses process for preparing such compound, pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases.

La présente invention englobe les nouveaux composés hétérocycliques substitués représentés par la formule (I) ou leurs sels pharmaceutiquement acceptables. La signification des substituants dans la formule (I) correspond à ce qui est défini dans la spécification. L'invention englobe également un procédé de préparation d'un tel composé, compositions pharmaceutiques et procédés de traitement ou de prévention de maladies induites par la PTP-1B.

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