Thiazolyl urea compounds for the treatment of cancer

Details Thiazolyl urea compounds for the treatment of cancer Thiazolyl urea compounds for the treatment of cancer

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) A61K 31/47 (2006.01) C07D 213/75 (2006.01) C07D 277/48 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01) C07D 453/02 (2006.01) C07D 453/06 (2006.01) C07D 471/04 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2476411

Selected thiazolyl urea compounds of formula (VI) are effective for prophylaxis and treatment of diseases, such as cell proliferation or apoptosis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving stoke, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

certains composés de thiazolyle urée ont une action prophylactique et curative efficace sur certaines maladies, telles les maladies induites par une prolifération cellulaire ou l'apoptose. Cette invention concerne des nouveaux composés, analogues, promédicaments, des sels de ces substances acceptables au plan pharmaceutique, des compositions pharmaceutiques et des méthodes de prophylaxie et de traitement de maladies et états impliquant une attaque, un cancer, etc. L'invention concerne également des procédés de fabrication de ces composés ainsi que des intermédiaires intervenant utilement dans ces procédés.

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