Thiophenepyrimidinones as 17-beta-hydroxysteroid...

C - Chemistry – Metallurgy – 07 – D

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C07D 495/14 (2006.01) A61K 31/55 (2006.01) A61P 35/00 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2527591

This invention relates to compounds useful in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent disorder, preferably a steroid hormone dependent disease or disorder requiring the inhibition of a 170.beta.-hydroxysteroid dehydrogenase (1 7.beta.-HSD) such as 17.beta.-HSD type 1, type 2 or type 3 enzyme.

L'invention concerne à des composés à usage thérapeutique, notamment dans le traitement et/ou la prévention d'un trouble lié aux hormones stéroïdes, de préférence une maladie liée aux hormones stéroïdes ou un trouble nécessitant une inhibition d'une 17.beta.-déhydrogénase hydroxystéroïde (17.beta.-HSD), notamment une enzyme 17.beta.-HSD de type 1, de type 2 ou de type 3.

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