Thrombin composition for oral administration

Details Thrombin composition for oral administration Thrombin composition for oral administration

A - Human Necessities

61

K

167/322, 167/103

A61K 47/42 (2006.01) A61K 38/48 (2006.01) A61K 47/16 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2037325

ABSTRACT OF THE DISCLOSURE A stable thrombin composition for oral administration having an excellent solubility is prepared with thrombin as a hemostatic ingredient, gelatin, albumin and glycine as a stabilizer and sucrose and/or sugar alcohol as a carrier. The thrombin composition is effective for the treatment of hemorrhage in the upper alimentary canal, is stable even at room temperature conditions for long periods of time, has excellent solubility and can be orally administered in a simple manner.

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