Tick polypeptides as anticoagulants and vaccines

Details Tick polypeptides as anticoagulants and vaccines Tick polypeptides as anticoagulants and vaccines

A - Human Necessities

61

K

A61K 39/00 (2006.01) C07H 21/04 (2006.01) C07K 14/435 (2006.01) C07K 16/18 (2006.01) C12N 9/00 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2497148

Polypeptides comprising tick polypeptides, portions and fragments thereof, including fusions, multimeric and chimeric proteins; nucleic acid molecules encoding them and antibodies directed against them. The various compositions are useful as anticoagulants, in compositions and methods for inducing tick immunity and preventing or reducing the transmission of tick-borne pathogens, and in diagnostic kits and methods.

La présente invention concerne des polypeptides, et notamment des polypeptides des tiques, certains de leurs fragments et de leurs parties, y compris des protéines de fusion, des protéines multimères et des protéines chimériques. L'invention concerne également des molécules d'acides nucléiques les codant et des anticorps dirigés contre eux. Ces diverses compositions conviennent comme anticoagulants, pour des compositions et pour des procédés visant à induire une immunité contre les tiques et à prévenir ou réduire la transmission de germes pathogènes portés par les tiques, et pour des nécessaires et procédés de diagnostic.

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