Tosylate salt of a 5-pyrazolyl-2-pyridone derivative, useful...

Details Tosylate salt of a 5-pyrazolyl-2-pyridone derivative, useful... Tosylate salt of a 5-pyrazolyl-2-pyridone derivative, useful...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/4439 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2752319

6-Methyl-5-(I -methyl-1H-pyrazol-5-yl)-N-{ [5-(methylsulfonyl)pyridin-2- yl]methyl }-2-oxo-1-[3-(trifluo- romethyl)phenyl]-1,2-dihydropyridine-3-carboxamide 4-methylbenzenesulfonate and a novel crystalline form thereof are dis- closed together with processes for preparing such salt and form, pharmaceutical compositions comprising such a form, and the use of such a salt and form in therapy.

La présente invention concerne le 6-méthyl-5-(I-méthyl-1 H-pyrazol-5-yl)-N-{[5-(méthylsulfonyl)pyridin-2-yl]méthyl}-2-oxo-1-[3-(trifluorométhyl)phényl]-1,2-dihydropyridine-3-carboxamide 4-méthylbenzènesulfonate et sa nouvelle forme cristalline ainsi que des procédés de préparation dudit sel et de ladite forme, des compositions pharmaceutiques comprenant ladite forme, et l'utilisation dudit sel et de ladite forme en traitement.

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