Transcription factors for differentiation of adult human...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/08 (2006.01)

Patent

CA 2661232

A method of transplantation that includes lineage priming human progenitor cells, to form lineage primed cells and transplanting the lineage primed cells into a patient. The lineage primed cells are selected from the group consisting of oligodendrocytic lineage primed cells, dopaminergic lineage primed cells, and motoneuronal lineage primed cells, and lineage priming has an efficiency of at least 1 %.

L'invention concerne un procédé de transplantation comportant un amorçage de lignée de cellules progénitrices humaines, pour former des cellules amorcées en lignée et transplanter les cellules amorcées en lignée sur un patient. Les cellules amorcées en lignée sont choisies dans le groupe constitué par des cellules amorcées en lignée oligodendrocytaires, des cellules amorcées en lignée dopaminergiques et des cellules amorcées en lignée motoneuronales; l'amorçage de lignée présente une efficacité d'au moins 1%.

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