C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/00 (2006.01) C07K 14/52 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2279573
Transgenic animals containing recombinant DNA with modified nucleotide sequence from the vascular endothelial growth factor B (VEGF-B) gene, cells and methods for producing such animals, and methods of using them to assay substances for VEGF-B-like activity.
L'invention concerne des animaux transgéniques qui contiennent un ADN recombinant avec une séquence nucléotidique modifiée du gène du facteur de croissance de l'endothélium vasculaire B (VEGF-B), des cellules et des méthodes qui permettent de produire lesdits animaux, ainsi que des méthodes qui permettent de les utiliser pour cribler des substances dans le but de détecter une activité de type VEGF-B.
Aase Karin
Betsholtz Christer
Eriksson Ulf
Gebre-Medhin Samuel
Li Xuri
Ludwig Institute For Cancer Research
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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