Transgenic fibrinogen

A - Human Necessities – 01 – K

Patent

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Details

A01K 67/027 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2347579

Transgenic non-human animals, capable of expressing a heterologous gene for human or other recombinant fibrinogen protein on subunit chain polypeptides thereof or modified fibrinogens in mammary glands of the animals and secreting the expressed product into a body fluid, are provided, as are methods of producing recombinant fibrinogens, subunit chains polypeptides thereof and modified fibrinogens, and fibrinogens fusion proteins in such animals.

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