Transgenic goat producing milk containing human...

Details Transgenic goat producing milk containing human... Transgenic goat producing milk containing human...

A - Human Necessities

01

K

A01K 67/027 (2006.01) C07K 14/535 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2396969

A transgenic goat zygote is developed from a goat zygote comprising a nucleic acid construct containing a nucleotide sequence of a goat .beta.-casein promoter and a nucleotide sequence encoding hG-CSF, which produces milk containing a high concentration of biologically active hG-CSF.

On développe, dans le cadre de cette invention, un zygote caprin transgénique à partir d'un zygote caprin, comprenant un produit de recombinaison d'acide nucléique contenant une séquence nucléotidique d'un promoteur de .beta.-caséine caprine ainsi qu'une séquence nucléotidique codant le facteur susmentionné (hG-CSF), ce qui permet de produire un lait à teneur élevée de hG-CSF actif du point de vue biologique.

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