A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/575 (2006.01) A61K 45/06 (2006.01) A61P 3/10 (2006.01) C07J 9/00 (2006.01)
Patent
CA 2665380
The present invention provides the use of an LXR antagonist, or a physiologically- acceptable pro-drug therefor, in the manufacture of a medicament for combating insulin resistance or a disorder associated therewith. Further provided is a compound being an ester or carbamate of a hydroxycholesterol, a pharmaceutical composition of such a compound or its use in therapy.
L'invention porte sur l'utilisation d'un antagoniste du LXR, ou sa prodrogue physiologiquement acceptable, pour la fabrication d'un médicament combattant la résistance à insuline ou un trouble associé. L'invention porte également sur un composé constitué d'un ester ou carbamate d'hydroxycholestérol, et sur un préparation pharmaceutique comprenant ledit composé et sur son utilisation à des fins thérapeutiques.
Brudeli Bjarne
Kase Eili Tranheim
Klaveness Jo
Nebb Hilde Irene
Rongved Pal
Freedman & Associates
Universitetet I. Oslo
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