C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/6518 (2006.01) A61K 31/4196 (2006.01) A61K 31/5355 (2006.01) C07F 9/6558 (2006.01)
Patent
CA 2695995
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
L'invention concerne des composés de triazole substitués et des compositions comprenant des composés de triazole substitués. L'invention concerne en outre des procédés d'inhibition de l'activité de HSP90 chez un sujet le nécessitant et des procédés pour empêcher ou traiter des troubles hyperprolifératifs, tels que le cancer, chez un sujet le nécessitant, comprenant l'administration au sujet d'un composé de triazole substitué de l'invention, ou d'une composition comprenant un tel composé.
Chimmanamada Dinesh U.
Koya Keizo
Li Hao
Przewloka Teresa
Sun Lijun
Gowling Lafleur Henderson Llp
Synta Pharmaceuticals Corp.
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