C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/4545 (2006.01) A61K 31/4745 (2006.01) A61K 31/497 (2006.01) A61K 31/4985 (2006.01) A61K 31/519 (2006.01) A61K 31/53 (2006.01) A61P 29/00 (2006.01) A61P 43/00 (2006.01) C07D 239/70 (2006.01) C07D 487/00 (2006.01) C07D 487/04 (2006.01) C07D 515/00 (2006.01)
Patent
CA 2319435
Novel triazolo derivatives including the one represented by formula (26), and pharmacologically acceptable salts thereof; and chemokine inhibitors containing the same as the active ingredient. These compounds are useful as remedies for allergic diseases including bronchial asthma and atopic dermatitis, inflammatory diseases including rheumatoid arthritis, and autoimmune diseases including nephritis and ulcerative colitis, or anti-AIDS drugs.
L'invention concerne de nouveaux dérivés triazolo, notamment le dérivé représenté par la formule (26), et des sels pharmaceutiquement acceptables de ces dérivés; ainsi que des inhibiteurs de chimiokines contenant ces dérivés comme ingrédient actif. Lesdits composés sont utilisés comme remèdes contre les affections allergiques, notamment l'asthme bronchique et la dermatite atopique, les maladies inflammatoires, notamment la polyarthrite rhumatoïde, et les maladies auto-immunes, notamment la néphrite et la rectocolite hémorragique, ou comme médicaments anti-SIDA.
Imaoka Takayuki
Kaneko Masayuki
Mori Noriko
Takahashi Toshiya
Tanida Koh
Smart & Biggar
Toray Industries Inc.
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