Tricyclic erythromycin derivatives

C - Chemistry – Metallurgy – 07 – H

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Details

C07H 17/08 (2006.01) A61K 31/70 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2235942

Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R1, R2 and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.

La présente invention concerne des composés, ou des sels et des esters de ces composés qui sont acceptables en pharmacie, selon les formules (I); (II); (III) ou (IV) dans lesquelles A, B, D et E, R<1>, R<2> et Z sont spécifiquement définis, présentant une activité antibactérienne, des compositions pharmaceutiques contenant les composés mentionnés, le traitement d'infections bactériennes avec lesdites compositions et des procédés de préparation des composés.

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