A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01)
Patent
CA 2562266
The present invention relates to a compound comprising a tripartite structure in the format C-B-A or C'-B'-A' wherein moiety A and moiety A' is a raftophile, moiety B and moiety B' is a linker, moiety C and moiety C' is a pharmacophore; and wherein moiety B and B' is a linker which has a backbone of at least 8 carbon atoms and wherein one or more of said carbon atoms may be replaced by nitrogen, oxygen or sulfur. Furthermore, specific medical and pharmaceutical uses of the compounds of the invention are disclosed.
L'invention concerne un composé comprenant une structure tripartite au format C-B-A ou C'-B'-A' dans laquelle la fraction A et la fraction A' consistent en un raftophile, la fraction B et la fraction B' consistent en un liant, la fraction C et la fraction C' consistent en un pharmacophore; et les fractions B et B' consistent en un liant possédant un squelette d'au moins 8 atomes de carbone dont un ou plusieurs de ces atomes de carbone peuvent être remplacé par de l'azote, de l'oxygène ou du soufre. L'invention concerne, en outre, les utilisations médicales et pharmaceutiques spécifiques de ces composés.
Braxmeier Tobias
Friedrichson Tim
Froehner Wolfgang
Jennings Gary
Knoelker Hans-Joachim
Jadolabs Gmbh
Jadolabs Technologies Gmbh
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.v.
Ridout & Maybee Llp
Technische Universitat Dresden
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