Trisubstituted piperidines

Details Trisubstituted piperidines Trisubstituted piperidines

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/538 (2006.01) A61P 9/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2702745

The application relates to trisubstituted piperidines of the general formula (I) and their salts, preferably their pharmaceutically acceptable salts, in which R1, R2, R3 and X have the meanings explained in the description, a process for their preparation and the use of these compounds as medicines, especially as renin inhibitors.

La présente invention concerne des pipéridines trisubstituées de formule générale (I) et leurs sels, de préférence leurs sels pharmaceutiquement acceptables, R1, R2, R3 et X ayant les significations explicitées dans la description. L'invention concerne également un procédé pour la préparation des pipéridines et de leurs sels et l'utilisation de ces composés comme médicaments, en particulier comme inhibiteurs de la rénine.

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