Tyrosine kinase inhibitors

Details Tyrosine kinase inhibitors Tyrosine kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) A61K 31/495 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/5355 (2006.01) A61P 7/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 487/04 (2006.01) C07D 487/08 (2006.01) C07D 491/08 (2006.01)

Patent

CA 2429728

The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.

L'invention concerne des composés qui inhibent, régulent et/ou modulent la transduction de signaux de tyrosine-kinase, des compositions qui contiennent ces composés, et des procédés concernant leur utilisation dans le cadre du traitement, chez les mammifères, de maladies et de conditions dépendantes de la tyrosine-kinase, telles que l'angiogenèse, le cancer, une croissance tumorale, l'athérosclérose, la dégénérescence maculaire relative à l'âge, la rétinopathie diabétique, les maladies inflammatoires et analogues.

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