Ultra high molecular weight polyethylene articles and...

A - Human Necessities – 61 – L

Patent

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A61L 27/16 (2006.01) A61K 31/355 (2006.01) C08L 23/06 (2006.01)

Patent

CA 2619502

The present invention generally provides implantable articles and methods of forming implantable articles from a crosslinked ultrahigh molecular weight polyethylene ("UHMWPE") blend stabilized with Vitamin E. The crosslinked UHMWPE blend may be prepared by combining the UHMWPE material and vitamin E prior to irradiating the UHMWPE blend with electron beam radiation at a sufficient radiation dose rate to induce crosslinking. The crosslinked UHMWPE blend may be incorporated into a variety of implants, and in particular, into endoprosthetic joint replacements

La présente invention concerne généralement des objets implantables et des procédés de fabrication d'objets implantables à partir d~un mélange de polyéthylène réticulé à ultra-haut poids moléculaire (« UHMWPE ») stabilisé avec de la vitamine E. Le mélange d~UHMPWPE peut être préparé en combinant le matériau d~UHMWPE et la vitamine E avant l~irradiation du mélange d~UHMWPE par une radiation de faisceau d~électrons à un taux de dose de radiations suffisant pour déclencher la réticulation. Le mélange d~UHMWPE réticulé peut être incorporé dans une variété d'implants, et en particulier dans le remplacement d~articulations endoprothétiques.

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