Ultra thin film transdermal/dermal or transmucosal/mucosal...

A - Human Necessities – 61 – F

Patent

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Details

A61F 13/00 (2006.01) A61F 15/00 (2006.01)

Patent

CA 2532981

An ultra thin film transdermal, dermal, transmucosal, mucosal pharmaceutical delivery system is disclosed, which has a handle adhered by a first adhesive to an ultra thin film layer. The opposite side of the ultra thin film is coated with a second adhesive layer, and carries an active ingredient. The handle adheres firmly to the ultra thin film layer, but does not adhere to skin, mucosa, or the silicone coated surface of a release liner. A portion of the handle extends beyond an edge of the ultra thin film to facilitate separation of the film from the release liner, and handling thereof. The second adhesive is more aggressive with respect to the patient's skin than the first adhesive is with respect to the surface of the ultra thin film, whereby the handle can be peeled away from the ultra thin film after the film has been applied to the patient.

L'invention concerne un système d'administration pharmaceutique en pellicule ultra-mince transdermique, dermique, transmucosal ou mucosal, comportant une poignée collée à une pellicule ultra-mince par l'intermédiaire d'un premier adhésif. Le côté opposé de la pellicule ultra-mince est revêtu d'une deuxième couche adhésive, et porte un agent actif. La poignée adhère fermement à la pellicule ultra-mince mais ne colle pas à la peau, la muqueuse ou la surface revêtue de silicone d'une doublure détachable. Une partie de la poignée s'étend au-delà d'un bord de la pellicule ultra-mince afin de faciliter le détachage de la pellicule par rapport à la doublure détachable, et la manipulation. Le deuxième adhésif est plus agressif par rapport à la peau que le premier adhésif ne l'est par rapport à la surface de la pellicule ultra-mince, la poignée pouvant ainsi être détachée de la pellicule ultra-mince après application de la pellicule sur le patient.

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