A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 37/00 (2006.01)
Patent
CA 2146010
A transdermal drug delivery system that uses ultrasonic energy to release a stored drug and forcibly move the drug through the skin of an organism into the blood stream of the organism is disclosed. The transdermal drug delivery system includes a housing (81) having a cavity (67) for storing the drug to be de- livered. The cavity is defined by an assembly of ultra- sonic transducers (65) and is separated from the skin by a polymeric membrane (69). The ultrasonic trans- ducer assembly includes a flat, circular ultrasonic transducer (85) that defines the top of a truncated cone and a plurality of transducer segments (87a, 87b, 87c, 87d...) that define the walls of the cone. The resonant frequency of the planar transducer is lower than the resonant frequency of the transducer seg- ments. Located between the transducer assembly and the cavity is a drug-impermeable laminate (77) that also functions as a focusing lens for the transducers. Control electronics (63) and a power source (61) are also stored in the housing. In operation, the planar, flat, circular transducer generates fixed frequency (5KHz-1MHz range) ultrasonic stimuli impulses for a predetermined period of time (10-20 seconds). Between the stimuli pulse periods, the transducer segments receive variable frequency ultrasonic pumping pulses. The transducer segments create beams that impinge on the skin at an oblique angle and create a pulsating wave. A skin temperature sensor is in- cluded to prevent the ultrasonic signals from overheating the skin. The system may also include an infrared (IR) or laser transdu- cer for enhancing the operation of the drug delivery system by heating the skin and creating additional ultrasonic waves. Both open loop and closed loop (feedback) versions are provided. The closed loop version includes a sensor for sensing drug delivery effectiveness and using the resulting information to control the rate of drug delivery. The sensor uses ultrasonic energy to remove fluid from the skin for analysis.
Endodermic Medical Technologies Company
Smart & Biggar
LandOfFree
Ultrasonic transdermal drug delivery system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Ultrasonic transdermal drug delivery system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ultrasonic transdermal drug delivery system will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1786141