Ultrasound imaging with targeted microbubbles

Details Ultrasound imaging with targeted microbubbles Ultrasound imaging with targeted microbubbles

A - Human Necessities

61

K

A61K 9/50 (2006.01) A61K 49/22 (2006.01)

Patent

CA 2684752

Compositions and methods for detecting various disorders with targeted microbubbles are disclosed. Specifically, microbubbles comprising glycoprotein Ib (GPIb), ligands for VCAM- 1, and ligands for P-selectin such as PSGL-1 are disclosed. Also disclosed are methods for using targeted microbubbles to detect cardiovascular disease comprising administering the disclosed microbubbles to a subject and detecting the microbubbles in the vasculature using ultrasound.

L'invention concerne des compositions et des procédés pour détecter divers troubles avec des microbulles ciblées.

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