C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/38 (2006.01) A01K 67/027 (2006.01) A61K 39/245 (2006.01) A61K 39/42 (2006.01) C07H 21/00 (2006.01) C07K 14/03 (2006.01) C07K 16/08 (2006.01) C07K 19/00 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01) G01N 33/574 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2261164
This invention provides an isolated nucleic acid molecule which encodes Kaposi's Sarcoma-Associated Herpesvirus (KSHV) polypeptides. This invention provides an isolated polypeptide molecule of KSHV. This invention provides an antibody specific to the polypeptide. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposi's Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.
L'invention a pour objet une molécule d'acide nucléique isolée qui code les polypeptides du virus de l'herpès associé au sarcome de Kaposi. Cette invention concerne une molécule de polypeptide isolée de virus de l'herpès associé au sarcome de Kaposi. L'invention traite aussi d'un anticorps spécifique au polypeptide, ainsi que des molécules d'oligonucléotides triplex et antisens. L'invention concerne aussi un vaccin pour le sarcome de Kaposi ainsi que des procédés pour la vaccination, la prophylaxie, le diagnostic et le traitement d'un sujet présentant un sarcome de Kaposi. L'invention traite également d'un procédé pour détecter l'expression d'un virus d'ADN associé au sarcome de Kaposi dans une cellule.
Bohenzky Roy A.
Chang Yuan
Edelman Isidore S.
Moore Patrick S.
Russo James J.
Gowling Lafleur Henderson Llp
The Trustees Of Columbia University In The City Of New York
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