Unsaturated acyclic phosphonate derivatives of purine and...

C - Chemistry – Metallurgy – 07 – F

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C07F 9/547 (2006.01) A61K 31/675 (2006.01) C07F 9/6512 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2078030

ABSTRACT This invention relates to novel unsaturated acyclic phosphonate derivatives of certain purines and pyrimidines of the formula: Image or Image Formula I Formula II the stereoisomeric forms and mixtures thereof, tautomeric forms and the pharmaceutically acceptable salts thereof, which are useful as antiviral agents, to methods and inter- mediates useful for their preparation and to their end-use application as antiviral agents effective against DNA vi- ruses, retroviruses and viruses involved in tumor forma- tion.

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