Urea and thiourea derivatives

Details Urea and thiourea derivatives Urea and thiourea derivatives

C - Chemistry, Metallurgy

07

D

C07D 215/38 (2006.01) A61K 31/352 (2006.01) A61K 31/4704 (2006.01) A61K 31/4709 (2006.01) A61P 5/28 (2006.01) C07D 311/14 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01)

Patent

CA 2515589

The invention is directed to a new class of quinolin-2-one and chromen-2-one compounds that have been derivatized at the 6-position with a urea or thio urea moiety of formula (I) in which M, R1, R2, X and A are as defined in the claims, and to their use as androgen antagonists.

L'invention se rapporte à une nouvelle classe de composés quinoline-zènes et z-exc chromènes qui sont dérivés en position-6 avec une urée ou cette fraction urée, et sont ensuite utilisés en tant qu'antagonistes androgènes.

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