Urea derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 211/06 (2006.01) C07D 211/14 (2006.01) C07D 211/46 (2006.01) C07D 295/096 (2006.01) C07D 295/14 (2006.01) C07D 405/12 (2006.01)

Patent

CA 1327200

Abstract of the invention : Urea derivatives of the following formula, Image wherein R1 indicates a piperidino group or pyrrolidino group which may be substituted with hydroxy group or lower alkyl group having 1 to 3 carbon atoms; A indicates an ethylene group, propy- lene group, butylene group or butenylene group; R2 indicates a straight or branched alkyl group having 1 to 20 carbon atoms, cycloalkyl group having 3 to 6 carbon atoms, benzyl group, or phenyl group which may have 1 to 3 substituents such as lower alkyl group having 1 to 6 carbon atoms, lower alkoxy group having 1 to 3 carbon atoms, halogen atom, trifluoromethyl group, amino group, nitro group or methylenedioxy group; X indicates an oxygen or sulfur atom, the hydrates and pharmaceutically acceptable acid addition salts thereof are useful as antiulcer agents.

573335

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