A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/236, 167/237
A61K 31/415 (2006.01) A61K 31/41 (2006.01) C07C 45/71 (2006.01) C07C 49/80 (2006.01) C07D 303/22 (2006.01) C07D 521/00 (2006.01)
Patent
CA 1229045
ABSTRACT OF THE DISCLOSURE The invention relates to the treatment of viral infections with hydroxyethylazolyl compounds of formula (I) Image (I) in which A represents a nitrogen atom or the CH group; R1 represents phenyl, phenoxymethyl, phenethyl or phenethenyl, each of which optionally has in the phenyl moiety one to three identical or different substituents selected from the group consisting of: halogen, alkyl having 1 to 4 carbon atoms, alkoxy and alkylthio, each having 1 or 2 carbon atoms, halogenoalkyl and halogenoalkoxy and halogenoalkylthio, each having 1 or 2 carbon atoms with 1 to 5 identical or different halogen atoms, phenyl and halogenophenyl; or R1 represents naphthyloxymethyl, 1,2,4-triazol-1-yl-methyl and imidazol-1- ylmethyl; R2 represents the group -C(CH3)2-R3, 1,2,4-triazol-1- yl-methyl or imidazol-1-yl-methyl and R3 represents methyl or R3 represents phenoxy or benzyl, both of which are optionally substituted by a member selected from the group consisting of halogen, alkyl having 1 to 4 carbon atoms, alkoxy and alkylthio, each having 1 or 2 carbon atoms, halogenoalkyl and halogenoalkoxy and halogenoalkylthio, each having 1 or 2 carbon atoms and 1 to 5 halogen atoms, phenyl and halogenophenyl; with the proviso that A does not represent a nitrogen atom at the same time as R1 represents p-chlorophenoxymethyl and R2 represents tert.-butyl, or physiologically tolerated acid addition salts.
452957
Buchel Karl H.
Elbe Hans-Ludwig
Holmwood Graham
Kraatz Udo
Paessens Arnold
Aktiengesellschaft Bayer
Fetherstonhaugh & Co.
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