Use of anethole dithiolethione in lung cancer chemoprevention

A - Human Necessities – 61 – K

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A61K 31/385 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2475545

The present invention relates to the use of 5-(p-methoxyphenyl)-1,2-dithiole-3- thione or of a pharmaceutical derivative thereof for the preparation of a medicament for preventing lung cancer in a mammalian subject, especially for preventing or reducing the appearance of new dysplastic lesions, or the progression of pre-existing dysplastic lesions in the subject, or for improving regression of existing dysplastic lesions.

La présente invention se rapporte à l'utilisation de 5-(p-méthoxyphényl)-1,2-dithiole-3-thione ou d'un dérivé pharmaceutique de ce composé pour la préparation d'un médicament permettant de prévenir le cancer du poumon chez un sujet mammalien, et permettant notamment d'empêcher ou de réduire l'apparition de nouvelles lésions dysplasiques, ou la progression de lésions dysplasiques préexistantes chez le sujet, ou encore d'améliorer la régression de lésions dysplasiques existantes.

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