Use of combination preparations containing thrombin receptor...

Details Use of combination preparations containing thrombin receptor... Use of combination preparations containing thrombin receptor...

A - Human Necessities

61

K

A61K 31/443 (2006.01) A61K 31/444 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2648613

Disclosed herein are pharmaceutical combinations comprising at least one thrombin receptor antagonist and at least one cardiovascular agent. Examples of cardiovascular agents suitable for co-formulation or co- administration with the thrombin receptor antagonist include an endothelin antagonist selected from the group consisting of tezosentan, bosentan, and sitaxsentan.

La présente invention concerne des associations pharmaceutiques comprenant au moins un antagoniste des récepteurs de la thrombine et au moins un agent cardiovasculaire. Parmi les exemples d'agents cardiovasculaires convenant pour une co-formulation ou une co-administration avec l'antagoniste des récepteurs de la thrombine figure l'antagoniste de l'endothéline, sélectionné parmi le groupe composé de tézosentan, bosentan et sitaxsentan.

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