A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/415 (2006.01) A61K 31/506 (2006.01)
Patent
CA 2410475
A method of promoting neuronal survival and helping prevent neuronal death administers (di-substituted-phenyl) pyrimidinyl imidazole derivative compounds represented by formula (I) effective to inhibit the activity of c-jun-N- terminal kinase.
L'invention concerne un procédé stimulant la survie des neurones et empêchant la mort des neurones, lequel consiste à administrer des composés de dérivés de (phényle disubstitué) pyrimidinyl imidazole représentés par la formule (I), qui sont efficaces pour inhiber l'activité des kinases c-jun-<i>N</i>-terminal.
Bilsland James G.
Harper Sarah J.
Lisnock-Geissler Jean-Marie
Lograsso Philip
Tam John
Merck & Co. Inc.
Merck Frosst Canada Inc.
Merck Sharp & Dohme Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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