Use of hypoglycemic agent for treating impaired glucose...

A - Human Necessities – 61 – K

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Details

A61K 31/198 (2006.01) A61K 31/195 (2006.01) A61P 5/50 (2006.01)

Patent

CA 2393083

The invention relates to the use of a hypoglycemic agent or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the prevention or delay of the progression to overt diabetes, especially type 2, prevention or reduction of microvascular complications (e.g. retinopathy, neuropathy, nephropathy), prevention or reduction of excessive cardiovascular morbidity (eg. myocardial infarction, arterial occlusive disease, atherosclerosis and stroke) and cardiovascular mortality, prevention of cancer and reduction of cancer deaths. Additionally, the invention relates to the use of a treatment for diseases and conditions that are associated with IGM, IGT or IFG.

La présente invention concerne l'utilisation d'un agent hypoglycémique ou un sel pharmaceutiquement acceptable de celui-ci pour fabriquer un médicament destiné à la prévention du diabète ou à retarder la progression de diabètes révélés, en particulier du type 2, à la prévention ou à la réduction de complications microvasculaires (par exemple la rétinopathie, la neuropathie, la néphropathie), à la prévention ou à la réduction de la morbidité excessive cardio-vasculaire (par exemple infarctus du myocarde, maladie à occlusion artérielle, athérosclérose et accident vasculaire cérébral) et de la mortalité par maladies cardio-vasculaires, à la prévention du cancer et à la diminution de la mortalité par cancer. Cette invention concerne aussi l'utilisation d'un traitement destiné à des maladies et à des pathologies associées au métabolisme du glucose défaillant, à la tolérance au glucose altérée ou à la glycémie à jeun.

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