Use of n-substituted phenothiazines

Details Use of n-substituted phenothiazines Use of n-substituted phenothiazines

C - Chemistry, Metallurgy

07

D

C07D 279/22 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07D 279/26 (2006.01) C07D 279/28 (2006.01) C07D 279/30 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2198256

The invention concerns the use of N-substituted phenothiazines for producing drugs for treating cerebral disorders. The invention also concerns novel active substances prepared by reacting phenothiazine with the appropriate acids, esters or amides or by reacting phenothiazine carboxylic acid halides with amines. The active substances are in particular suitable for treating dementia, depression and learning and memory disorders caused by old age.

L'invention concerne l'utilisation de phénothiazines substituées par N, pour la production de médicaments destinés au traitement des maladies cérébrales. L'invention concerne également de nouveaux principes actifs fabriqués par réaction de phénothiazine avec des acides, esters ou amides appropriés ou par réaction d'halogénure d'acide carboxylique de phénothiazine avec des amines. Ces principes actifs sont utilisés en particulier dans le traitement des démences ainsi que des troubles de la mémoire et des facultés d'apprentissage, liés à la vieillesse, et des dépressions.

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