Use of pyrazole carboxamides

Details Use of pyrazole carboxamides Use of pyrazole carboxamides

A - Human Necessities

61

K

A61K 31/4155 (2006.01) A61K 31/415 (2006.01) A61K 31/443 (2006.01) A61P 7/06 (2006.01) C07D 231/12 (2006.01) C07D 401/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2361636

The present invention relates to novel and known pyrazole carboxamides of general formulae (I and Ia), whereby A, A', D, D', E, E', G, G', R1, R'1, R2 and L have the meaning as given in the description. The invention also relates to the production of pyrazole carboxamides by means of solid phase chemistry or novel pyrazole carboxamides. The pyrazole carboxamides are used as medicaments, especially (oral) medicaments for the treatment of anaemias. Said carboxamides stimulate the EPO production (erythropoesis) and can be used with own blood donors.

L'invention concerne des amides d'acides pyrazol-carboxyliques, de formules générales (I) et (Ia), dont certains sont nouveaux et d'autres connus, ainsi que la fabrication desdits amides soit par la chimie en phase solide, soit par l'intermédiaire des nouveaux acides pyrazol-carboxyliques. Ces amides peuvent être utilisés comme médicaments, notamment pour le traitement de l'anémie.

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