Use of pyridazino[4,5-b]indole-1-acetamide derivatives for...

A - Human Necessities – 61 – K

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A61K 31/5025 (2006.01) A61P 9/00 (2006.01) A61P 13/12 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2360754

The invention concerns the use of a compound of general formula (I) wherein: X represents a halogen atom; Y represents one or several atoms or groups selected among hydrogen, halogens and hydroxy, methyl, methoxy and nitro groups; R 1 represents a C 1 -C 4 alkyl group; R 2 and R 3 represent each a hydrogen atom or a C 1 -C 4 alkyl group, or R 2 and R 3 together form with the nitrogen atom bearing them, a pyrrolidinyl, piperidinyl or morpholinyl group, for preparing a medicine for preventing or treating diseases and disorders related to the peripheral benzodiazepin receptor.

Utilisation d'un composé de formule générale (I) dans laquelle X représente un atome d'halogène, Y représente un ou plusieurs atomes ou groupes choisis parmi l'hydrogène, les halogènes et les groupes hydroxy, méthyle, méthoxy et nitro, R1 représente un groupe (C1-C4)alkyle, R2 et R3 représentent chacun un atome d'hydrogène ou un groupe (C1-C4)alkyle, ou bien R2 et R3 forment, avec l'atome d'azote qui les porte, un groupe pyrrolidinyle, pipéridinyle ou morpholinyle, pour la préparation d'un médicament destiné à la prévention et au traitement des maladies et troubles liés au récepteur benzodiazépinique périphérique.

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