A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/47 (2006.01) A61P 31/18 (2006.01)
Patent
CA 2489102
The invention concerns the use of 8-hydroxyquinoline 7-carboxylic acid derivatives for making integrase inhibiting medicines, capable of blocking viral replication at the stages preceding integration, and as the case may be at said integration stage, said medicines being usable for the treatment of retroviral pathologies, in particular for treating AIDS.
L'invention vise l'utilisation de dérivés de l'acide 8-hydroxyquinoléine 7- carboxylique pour fabriquer des médicaments inhibiteurs d'intégrase, capables de bloquer la réplication virale aux étapes précédant l'intégration, et le cas échéant au niveau de cette étape d'intégration, ces médicaments étant utilisables pour le traitement de pathologies rétrovirales, en particulier pour le traitement du Sida.
Bonnenfant Sabine
D'angelo Jean
Dargemont Catherine
Desmaele Didier
Leh Herve
Bioalliance Pharma
Centre National de La Recherche Scientifique (cnrs)
Institut Gustave Roussy
Institut National de La Sante Et de La Recherche Medicale (inser
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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