Use of the site-specific integrating function of phage oc31

Details Use of the site-specific integrating function of phage oc31 Use of the site-specific integrating function of phage oc31

C - Chemistry, Metallurgy

12

N

195/86, 195/1.23

C12N 15/76 (2006.01) C12N 1/21 (2006.01) C12N 9/10 (2006.01) C12N 15/11 (2006.01) C12N 15/52 (2006.01) C12N 15/90 (2006.01) C12P 1/06 (2006.01) C12P 19/62 (2006.01)

Patent

CA 2018164

X-7584 Abstract The present invention provides a method for transforming an actinomycete with an integrating vector which has the advantages of high transformation rates into a broad host range, site-specific integration, and stable maintenance without antibiotic selection. Also provided are methods for the increased production of antibiotics and for the production of hybrid anti- biotics.

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