Use of thienopyrimidines

Details Use of thienopyrimidines Use of thienopyrimidines

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/505 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2544550

The invention relates to compounds of formula (I), wherein R1, R2, R3, R4, X and n have the meanings cited in claim (1). Said compounds are inhibitors of tyrosinkinases, especially TIE-2, and Raf- Kinases and can be used, for example, in the treatment of tumours.

L'invention concerne les composés représentés par la formule (I) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, X et n ont les significations données dans la revendication (1). Lesdits composés sont des inhibiteurs de tyrosine-kinases, notamment de TIE-2, et de Raf-kinases, et peuvent par exemple être employés dans le traitement de tumeurs.

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