Vaccination against host cell-associated herpesviruses

Details Vaccination against host cell-associated herpesviruses Vaccination against host cell-associated herpesviruses

C - Chemistry, Metallurgy

12

N

C12N 15/38 (2006.01) A61K 31/70 (2006.01) A61K 39/112 (2006.01) C07K 14/055 (2006.01) C12N 1/21 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2417923

The invention relates to the field of so-called host cell-associated herpesviruses such as Marek's disease like virus (MDV) of poultry and of Varicella Zoster virus (VZV) of man and to vaccination against disease caused by these viruses. The invention provides a vaccine directed against an infection caused by an herpesvirus that is essentially host cell associated comprising a recombinant viral genome derived from said herpesvirus, said genome allowing recombination essentially free of said host cell.

L'invention concerne le domaine des herpèsvirus associés à une cellule hôte, tels que le virus du type maladie de Marek des poules et le virus varicella-zona de l'homme, ainsi que la vaccination contre les maladies provoquées par ces virus. L'invention concerne un vaccin dirigé contre une infection provoquée par un herpèsvirus, lequel est essentiellement associé à une cellule hôte, ce vaccin comprenant un génome viral recombiné, dérivé dudit herpès virus et permettant une recombinaison de manière essentiellement indépendante de la cellule hôte.

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