Vaccination methods

Details Vaccination methods Vaccination methods

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 35/76 (2006.01) A61K 39/02 (2006.01) A61K 39/12 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2755790

In one aspect, a method of treating cancer in a mammal is provided. The method comprises administering to the mammal an oncolytic vector that expresses a tumour antigen to which the mammal has a pre-existing immunity. In another aspect, a method of boosting immune response in a mammal having a pre-existing immunity to an antigen is provided comprising intra-venous administration to the mammal of a B-cell infecting vector that expresses the antigen.

Dans un aspect, l'invention concerne un procédé de traitement du cancer chez un mammifère. Le procédé comprend l'administration au mammifère d'un vecteur oncolytique qui exprime un antigène tumoral contre lequel le mammifère est déjà immunisé. Dans un autre aspect, l'invention concerne un procédé de stimulation de la réponse immunitaire chez un mammifère étant déjà immunisé contre un antigène, qui comprend l'administration intraveineuse au mammifère d'un vecteur infectant les cellules B qui exprime l'antigène.

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