C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/465 (2006.01) A61K 39/385 (2006.01)
Patent
CA 2649631
The present invention provides a hapten in the form o f a novel nicotine derivative that may suitably be conjugated with an appropriate carrier to yield an effective vaccine against nicotine addiction. More particularly, the invention relates to a nicotine derivative of the following formula (I): The present invention also relates to a hapten-carrier conjugate derived from the aforementioned nicotine derivative and a vaccine composition comprising said hapten-carrier conjugate.
L'invention concerne un haptène sous forme de nouveau dérivé nicotinique pouvant être conjugué de manière appropriée avec un excipient adéquat afin d'obtenir un vaccin efficace contre la dépendance à la nicotine. L'invention concerne plus particulièrement un dérivé nicotinique de formule suivante (I). L'invention concerne également un conjugué haptène-excipient dérivé dudit dérivé nicotinique et une composition de vaccin comprenant ledit conjugué haptène-excipient.
Hoogerhout Peter
Zomer Gijsbert
de Staat Der Nederlanden Vert. Door de Minster Van Vws
Ridout & Maybee Llp
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