Vaccines based on targeting antigen to dcir expressed an...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/28 (2006.01) A61K 35/12 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61P 37/04 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2715044

The present invention includes compositions and methods for increasing the effectiveness of antigen presentation using a DCIR-specific antibody or fragment thereof to which an antigen is attached that forms an antibody-antigen complex, wherein the antigen is processed and presented by a dendritic cell that has been contacted with the antibody-antigen complex.

La présente invention comprend des compositions et des procédés pour augmenter l'efficacité d'une présentation d'antigène en utilisant un anticorps spécifique au DCIR ou un fragment de celui-ci auquel un antigène est attaché formant un complexe anticorps-antigène, l'antigène étant traité et présenté par une cellule dendritique qui a été mise en contact avec le complexe anticorps-antigène.

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