Vanadyl complexes of hydroxamate chelators and...

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 9/00 (2006.01) A61K 31/28 (2006.01)

Patent

CA 2097608

2097608 9307155 PCTABS00021 Vanadyl complexes of chelating dihydroxamate compounds suitable for oral treatment of diabetes are disclosed. The dipodal hydroxamate ion carriers effectively bind and transport vanadyl ions across lipid membranes and potentiate glucose metabolism. The complexes may be generated in vivo by administration of a vanadyl salt and the hydroxamate ion carrier.

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