Variant c-terminal fragment of plasmodium falciparum msp-1

Details Variant c-terminal fragment of plasmodium falciparum msp-1 Variant c-terminal fragment of plasmodium falciparum msp-1

C - Chemistry, Metallurgy

12

N

C12N 15/30 (2006.01) A61K 39/015 (2006.01) C07K 14/445 (2006.01) C07K 16/20 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2271451

A non-naturally occurring variant of a C-terminal fragment of a Plasmodium merozoite surface protein-1 (MSP-1) wherein said variant has (i) a reduced affinity, compared with a naturally occurring Plasmodium MSP-1 19, for at least one first antibody capable of blocking the binding of a second antibody, which second antibody inhibits the proteolytic cleavage of Plasmodium MSP-1 42 and (ii) substantially the same affinity for at least one third antibody compared with said naturally occurring Plasmodium MSP-1 19. which third antibody inhibits the proteolytic cleavage of Plasmodium MSP-1 42 is provided for use in an anti-malarial vaccine.

Affiliated with

Also associated with

Rating

Variant c-terminal fragment of plasmodium falciparum msp-1 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Variant c-terminal fragment of plasmodium falciparum msp-1, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Variant c-terminal fragment of plasmodium falciparum msp-1 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1559507