Vasopressin-binding l-nucleic acid

Details Vasopressin-binding l-nucleic acid Vasopressin-binding l-nucleic acid

C - Chemistry, Metallurgy

07

H

C07H 21/02 (2006.01) A61K 31/7088 (2006.01) A61P 3/12 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07H 21/00 (2006.01) C07K 7/16 (2006.01) C12N 15/11 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2588980

The invention relates to a vasopressin-binding nucleic acid, characterized in that the nucleic acid has a Box 1 segment and a Box 2 segment, Box 1 having the sequence GUGGW, in which W = A or U, preferably W = U, and Box 2 having a sequence comprised of approximately 18 to 24 nucleotides, preferably 21 nucleotides, and a group (G)n being contained four times in the sequence, whereby n = 2, 3 or 4.

L'invention concerne un acide nucléique liant la vasopressine, qui se caractérise en ce que ledit acide nucléique comprend une section de boîte 1 et une section de boîte 2. La boîte 1 comporte la séquence GUGGW et W = A ou U, plus particulièrement, W = U et la boîte 2 comporte une séquence composée de 18 à 24 nucléotides, plus particulièrement 21 nucléotides, et un groupe (G)n est contenu quatre fois dans la séquence, n = 2, 3, ou 4.

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