C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/327, 260/520
C07D 498/04 (2006.01) C07D 241/08 (2006.01) C07D 339/00 (2006.01) C07D 505/00 (2006.01) C07D 519/00 (2006.01) C07F 9/535 (2006.01)
Patent
CA 1219866
- 1 - Abstract: The invention discloses compounds of the formula: Image (I) wherein u represents hydrogen, carboxamido, N-hydroxy- carboxamido, carboxy, azido, an aryl, an acylamino, a protected carboxy or an N-alkoxycarboxamido, or, together with v, can represent -S- or -CH2S-; v represents hydrogen, halogen, cyano or an alkylthio, or, together with u, can represent -S- or -CH2S-, or, together with w, can represent -(CH2)3CO-; w represents hydrogen, carbamoyl, cyano, carboxy, an N-alkylcarbamoyl, an alkyl, an aryl, a protected carboxy or a heterocycle, or, together with v, can represents -(CH2)3CO-; x represents halogen, trifluoro- methyl, an alkylthio or an arylthio; y represents hydrogen, a light metal or a carboxylic acid protecting group; and z represents an acyloxy or a heterocycle-thio, each of the above radicals represented by the symbols u, v, w, x, y and z being optionally substituted by halogen or a carbon-, nitrogen-, oxygen- or sulfur-containing functional group. These compounds exhibit a strong antibiotic activity to various microorganisms and are chemically stable.
437258
Aoki Tsutomu
Konoike Toshiro
Kubota Tadatoshi
Nagata Wataru
Nishitani Yasuhiro
Kirby Eades Gale Baker
Shionogi & Co. Ltd.
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