Vitamin d receptor modulators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 333/70 (2006.01) A61K 31/559 (2006.01) A61P 3/14 (2006.01) C07D 333/68 (2006.01)

Patent

CA 2544522

The present invention relates to novel, non-secosteroidal, phenyl- benzothiophene compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1.alpha.,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.

La présente invention concerne de nouveaux composés de phényl-benzothiophène non sécostéroïdes pouvant moduler le récepteur de la vitamine D (VDR), qui sont moins hypercalcémiques que la vitamine D3 1.alpha.25? ¿dihydroxy. Ces composés sont utiles pour le traitement de maladies osseuses ou du psoriasis.? ¿

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