Vitronectin receptor antagonists

Details Vitronectin receptor antagonists Vitronectin receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/52 (2006.01) A61K 31/55 (2006.01) A61K 33/24 (2006.01) A61K 45/06 (2006.01) C07D 223/16 (2006.01) C07D 233/56 (2006.01) C07D 233/64 (2006.01) C07D 235/18 (2006.01) C07D 235/22 (2006.01) C07D 243/14 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 487/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2267224

Compounds having a benzodiazepinyl core structure are disclosed which are vitronectin receptor antagonists useful in the treatment of osteoporosis, angiogenesis, tumor growth and metastasis, atherosclerosis, restenosis and inflammation.

L'invention concerne des composés, dotés d'une structure centrale benzodiazépinyle, qui sont des antagonistes du récepteur de la vitronectine, utiles dans le traitement de l'ostéoporose, de l'angiogenèse, de la croissance tumorale et de la dissémination métastasique de l'athérosclérose, de la resténose, et des inflammations.

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