W-amino-.alpha.-phenylalkanonitrile derivatives

C - Chemistry – Metallurgy – 07 – C

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C07C 255/32 (2006.01) A61K 31/275 (2006.01) C07C 255/43 (2006.01) C07C 323/63 (2006.01)

Patent

CA 2032872

Case 2592 .omega.-AMINO-.alpha.-PHENYLALKANONITRILE DERIVATIVES ABSTRACT A class of .omega.-amino-.alpha.-phenylalkanonitrile derivatives is described having use in treatment of cardiovascular dysfunctions such as hypertension. Compounds of most interest are those of the formula: Image wherein each of R1 and R2 is methoxy, R3 is hydrido, R4 is isopropyl, R5 is methyl and R6 is selected from linear alkyl, phenylpropyl, phenylbutyl and phenylpentyl.

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